Ph.D. in Medicinal Chemistry, Organic Chemistry, Chemical Biology, Biochemistry, or a related field, with either (i) 0–3 years of relevant postdoctoral……
Develop and characterize highly-productive CHO cell culture processes suitable for cGMP biotherapeutic manufacturing within project timelines, performing……
Serve as a Multispecifics Engineering representative in cross-functional teams including the Therapeutic Area, Discovery Biotherapeutics, and Development……
Process Engineering also partners with Biologics CMC (Chemistry, Manufacturing, and Controls) Development and Aesthetics R&D functions to provide active……
Equivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and……
To be considered for this role you must have a PhD in molecular biology, cell biology, biochemistry, immunology or a related field with at least one year of……
Develops understanding of specialized scientific or engineering field. Provides expertise in support of research projects in engineering, biology, mathematics,……
Demonstrated ability to apply knowledge of cell biology, chemical engineering, or bioengineering toward process development, scale-up /scale-down and……
Employees also have access to internal and state-sponsored training as well as reduced tuition for state-supported courses at all State of South Dakota academic……
A PhD in chemical engineering or a closely related engineering field is ideal; peer-reviewed publications, process simulations, lab-scale or pilot-plant……
Proficiency in scientific software and data analysis tools. You will serve as a subject matter expert (SME), driving innovation and excellence in analytical……
Proficiency in scientific software and data analysis tools. You will serve as a subject matter expert (SME), driving innovation and excellence in analytical……
The successful candidate will work in the DOE-funded ‘Integrating cell-free systems and genome engineering to accelerate biosystems design for carbon-negative……
PhD in bioengineering, biochemistry, structural biology, molecular biology, cell biology, or a related field. Excellent problem-solving skills, with the ability……
PhD or equivalent experience in protein biochemistry, molecular biology, biological engineering, or a related field. Annual performance-based target bonus.…
BA or BS in biology, chemistry, physics or other relevant field. You may excel in this role if you enjoy using an engineering mindset in wet lab biology,……
These powerful models rely on extensive biological and computational infrastructure and allow insitro to advance novel targets and patient biomarkers, design……
Master’s degree in Chemistry, Chemical Engineering, Pharmaceutical Engineering or related field. Operate plate reader for method development, method validation……
This individual will design and carry out experiments and provide technical leadership to associates, explore new technologies to speed up process development……
In this fast-paced, technical milestone-oriented role, you will have a breadth of opportunities to acquire diverse experiences & skills with enzyme development,……
Of particular interest is peptide engineering, enzyme engineering and molecular mechanics modeling. This Individual: You should have a minimum of a masters……
This Individual: You should have a minimum of a masters degree and five years recent experience or a Ph.D. degree and two years recent experience in the……
We are seeking a highly motivated Research Scientist with strong protein production and engineering expertise, who can focus on driving innovative, new……
Ph.D. in a relevant field (radiochemistry, radiobiology, chemistry, biology, molecular imaging, radiotherapy, or related field) obtained within the last four……
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Kodiak Sciences Inc. is a fast-growing, clinical-stage biopharmaceutical company focused on transforming ophthalmology through innovative therapeutics. Our Antibody Biopolymer Conjugate Drug (ABCD) platform integrates protein and peptide engineering & discovery, polymer chemistry, small molecule drug discovery, bioconjugation, and drug delivery technologies to address high-prevalence ophthalmic diseases.
We are seeking a talented Scientist/Senior Scientist to advance peptide therapeutic drug discovery and development programs with a strong emphasis on molecular design, organic synthesis, and analytical characterization.
Key Responsibilities
Lead the design, synthesis, and optimization of peptide-based therapeutics, integrating Structure-Activity Relationship (SAR) considerations, developability and conjugation strategies to drive candidate progression.
Perform hands-on experimental work including, but not limited to DNA-Encoded Library synthesis, Macrocyclic and Linear Peptide synthesis, polymer conjugation chemistry, purification and analytical evaluation, data interpretation and developability risk assessment.
Develop and apply analytical and biophysical methods (e.g., LC-MS, HPLC, NMR, SEC, DLS) to characterize peptides and bioconjugates, including purity, heterogeneity, stability, and aggregation.
Collaborate cross-functionally and communicate scientific findings through presentations, reports, and regulatory documentation.
Education / Qualifications
Ph.D. in Medicinal Chemistry, Organic Chemistry, Chemical Biology, Biochemistry, or a related field, with either (i) 0–3 years of relevant postdoctoral experience and at least one first-author publication in a high-impact, peer-reviewed journal (preferred), or (ii) 3+ years of relevant industry experience.
Experience working with either of the following methodologies, such as Solid Phase Peptide Synthesis (SPPS), DNA-Encoded Library (DEL) synthesis, liquid phase parallel synthesis and/or polymer-based bioconjugates is highly desirable.
Strong experience in therapeutic development of peptides, and/or conjugated biologics, experience in analytical characterization is a plus.
Proficiency in chromatographic and mass spectrometry-based techniques, with an understanding of developability attributes such as stability, solubility, and manufacturability is a plus.
Experience in using software such as PyMol, MOE, Schrödinger, Maestro, DataWarrior, Vortex is a plus.
Experience with CD and/or FTIR for peptide secondary structure determination is a plus.
Hands-on experience with biochemical assays, including SPR, ELISA, fluorescence-based assays, is a plus.
Demonstrated ability to independently drive scientific work in a collaborative, cross-functional environment, with strong problem-solving and communication skills.
The minimum salary is $123K and the max salary is $184K.
$123K – $184K/yr (Glassdoor est.)
$150K
/yr Median
Palo Alto, CA
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