Notifications

Are you open to new opportunities?

Upload your resume to increase your chances of getting noticed.

Ultragenyx
3.4
Executive Director, CMC QA
South San Francisco, CA
$294K - $363K (Employer provided)
Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.…
3d
Ultragenyx
3.4
Director, Biostatistics
Novato, CA
$221K - $273K (Employer provided)
The Director of Biostatistics acts as program statistical lead; provides technical leadership and biostatistical support on the design and conduct of clinical……
4d
Ultragenyx
3.4
Associate Director, Global Medical Communications
Novato, CA
$191K - $236K (Employer provided)
Collaborate with Medical Information and other Medical Affairs colleagues to ensure scientific accuracy and message consistency across standard responses,……
30d+
PlayStation
4.2
Game Engineering Director
Remote
$255K - $383K (Employer provided)
Collaborate with a cross-disciplinary project leadership team to develop and maintain a product technology strategy that is informed by product vision,……
30d+
director engineer jobs in Remote Remote jobs PlayStation jobs in Remote
PlayStation salaries director engineer salaries in Remote
Employee reviews at PlayStation PlayStation interview experience Working at PlayStation
GiveDirectly
4.0
Director of Engineering (Remote)
United States
Strong technical judgment driven by the mission, not ego: you can pressure-test architecture decisions with very senior engineers, have made consequential calls……
27d
director engineer jobs in United States GiveDirectly jobs in United States
GiveDirectly salaries
Employee reviews at GiveDirectly GiveDirectly interview experience Working at GiveDirectly
Affinity Health Management
3.0
GIP Medical Director Hospitalist
Des Moines, IA
$145K - $271K (Glassdoor est.)
Easy Apply
Licensed as a Doctor of Medicine or Osteopathy in the state without restriction or subject to any disciplinary or corrective action.…
30d+
Amberwell Health
3.4
Director of Emergency Care
Hiawatha, KS
$57K - $98K (Glassdoor est.)
Ensures compliance with certification and accreditation standards in accordance with Amberwell policies and procedures. Attends other meetings as necessary.…
20d
Lynn Community Health Center
3.5
Team Medical Director
Lynn, MA
$120K - $250K (Employer provided)
Easy Apply
Physician, Nurse Practitioner or Physician Assistant, Board Certified, with Massachusetts license. Experience in medical administration, particularly evaluation……
30d+
Cook Children's Health Care System
4.2
Director, Epilepsy Research
Fort Worth, TX
$60K - $102K (Glassdoor est.)
Cook Children's Director of Epilepsy Research is a core member of the Research team responsible for developing and leading a research program focused on……
30d+
Galvion
2.2
Director of Engineering
Portsmouth, NH
$160K - $222K (Glassdoor est.)
Easy Apply
Deep understanding of electrical, software, mechanical and/or industrial design, allowing for credible technical oversight.…
13d
The Forest at Duke
3.1
Assistant Director of Nursing
Durham, NC
$77K - $101K (Glassdoor est.)
Responsible for providing developing, implementing, and facilitating education programs for the Health Services department in accordance with current federal,……
30d+
Jordan Valley Community Health Center
2.9
PACE Medical Director, Jordan Valley Senior Care
Springfield, MO
$40K - $72K (Glassdoor est.)
Easy Apply
Education: M.D. or DO with current state of license. Qualified Candidates MUST be a M.D. or DO with current state of license. Provides oversight of the QI Plan.…
30d+
Nemours Children's Health
3.7
Director, Value Analysis and Strategic Sourcing (RN)
Wilmington, DE
$68K - $107K (Glassdoor est.)
RN licensure within the state of Delaware or Florida, or multi-state Enhanced Nursing License Compact (eNCC). This is a new role that will enhance / improve the……
5d
Concentra
3.3
Physician Clinic Medical Director
Philadelphia, PA
Qualifications - Active and unrestricted medical license - Unrestricted DEA license and dispensing license for state of jurisdiction (required prior to start……
30d+
Shermco Industries
3.5
Director of Transformation
Irving, TX
$160K - $190K (Employer provided)
This role converts insights into action by driving disciplined execution, advanced analytics, and cross-functional collaboration to deliver measurable results.…
12d
Recover-Care Heartland
3.0
Assistant Director of Nursing (ADON)
Blue Rapids, KS
$68K - $92K (Glassdoor est.)
Easy Apply
Responsible for competency testing on registered, licensed, certified, and non-certified nursing personnel. Design systems to plan, promote, develop, assess,……
7d
Trilogy Health Services
4.3
Director of Rehabilitation
Sun Prairie, WI
$34.00 - $47.00 Per Hour (Employer provided)
Must have and maintain a current, valid state licensure in respective discipline. Meets the requirements of specific therapy discipline to deliver skilled rehab……
11d
UNC Health
3.8
WMC Pharmacy Director
Boone, NC
$108K - $152K (Glassdoor est.)
Active Pharmacist license in the State of North Carolina required. Lead and develop pharmacy staff, fostering a positive and high-performing work environment.…
30d+
The Bay at Burlington
3.0
Director of Therapy
Laona, WI
$130K (Employer provided)
Easy Apply
Recommend modifications or changes in the resident’s therapy program based on own evaluation of progress. Assume responsibility for ongoing continuing education……
9d
Steele Memorial Medical Center
3.2
Director of Surgical Services
Salmon, ID
$85K - $114K (Glassdoor est.)
RN licensure required in the state of Idaho; BSN preferred. Current BLS and ACLS certification required. Provides technical consultation and support to Surgical……
2d
Concentra
3.3
Physician Clinic Medical Director
Austin, TX
$20K (Employer provided)
Unrestricted DEA license and dispensing license for state of jurisdiction (required prior to start date). Active and unrestricted medical license.…
30d+
Bethel Family Clinic
2.3
Medical Director
Bethel, AK
$175K - $250K (Employer provided)
Easy Apply
*Licenses, Certifications*: Current Alaska Advanced Practice Registered Nurse (APRN) license, or ability to obtain licensure in the State of Alaska.…
30d+
Newport Healthcare
2.6
Medical Director Psychiatrist
Saint Cloud, MN
$350K - $425K (Employer provided)
Easy Apply
Conduct thorough psychiatric evaluations within 48 hours of admission. Provide support for patient admissions, including initial evaluations and assessments.…
30d+
Steele Memorial Medical Center
3.2
Director of Patient Financial Services
Salmon, ID
Bachelor's degree in business Administration, finance, or related field along with 3-5 years of progressive experience in healthcare revenue cycle management……
6d
Worthington Woods Animal Care Center
5.0
Medical Director
Columbus, OH
$150K - $170K (Employer provided)
Ohio veterinary license (or ability to obtain). Paid license renewals, membership dues, and AVMA PLIT coverage. Annual CE allowance + CE days.…
19d
Widespread Whole Life Recovery
Medical Director
Springfield, IL
$150.00 - $200.00 Per Hour (Employer provided)
Easy Apply
Active, unrestricted Illinois medical or advanced‑practice license in good standing. Provide proof of current malpractice insurance, Illinois license, and any……
4d
Doctors For Providers
Dermatologist - Collaborating Physicians and Medical Directors (for board certified US physicians)
Remote
$3K - $24K (Employer provided)
Easy Apply
Looking for licensed and board certified dermatologists to be Medical Directors and Collaborating Physicians. Have needs in all 50 states.…
30d+
State of Washington
3.4
Facility Medical Director - AHCC
Airway Heights, WA
$130K - $338K (Employer provided)
Unrestricted license to practice medicine in Washington State. Board certification in the ABMS/ABOM certified specialty with Internal Medicine preferred.…
30d+
Best Friends Animal Society
3.4
Veterinarian Medical Director
United States
$175K (Employer provided)
Where required under applicable law, the company provides eligible employees with paid sick leave, health emergency leave, and similar benefits programs, all in……
16d
Penfield Search Partners
5.0
Director Biostatistics - Oncology
San Francisco, CA
Easy Apply
They are currently seeking a highly skilled and experienced Director of Biostatistics to provide leadership to develop and execute statistical strategy, design……
30d+

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Is your resume a good match?

Use AI to find out how well the skills on your resume fit this job description.

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won't go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

The Executive Director, CMC QA will provide strategic, operational, and technical quality leadership across all Ultragenyx programs inclusive of biologics, small molecule, gene therapy, and ASO. This leader will oversee CMC QA responsibilities spanning program QA and CMO QA for starting materials, drug substance, and drug product, ensuring phase-appropriate and commercially robust quality oversight from development through lifecycle management. The role will lead and develop a team of approximately 8–12 quality professionals, partner closely with Technical Operations, Product Development, Supply Chain, Regulatory, and Quality stakeholders, and represent CMC QA in governance forums, inspections, regulatory submissions, and external partner interactions.

Work Model:

Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.

Responsibilities:

Set and execute the CMC QA vision, strategy, operating model, and priorities for External Operations across all Ultragenyx programs and modalities, including starting materials, drug substance, and drug product.

Lead, coach, and develop a high-performing team of approximately 8–12 staff members responsible for program QA and CMO QA oversight; establish clear accountabilities, resource plans, succession plans, and performance expectations.

Ensure external partners operate in compliance with FDA, EMA, ICH, and other applicable global regulatory requirements, Ultragenyx Quality standards, approved regulatory filings, quality agreements, and industry best practices.

Drive proactive, risk-based oversight of external manufacturing quality systems, including deviations, investigations, CAPAs, change controls, complaints, product impact assessments, APR/PQR/APQR, CPV, validation, and tech transfer activities.

Own or oversee quality risk management strategies for external operations, including risk profiles, risk controls, escalation pathways, quality metrics, scorecards, trend reviews, and continuous improvement plans for CMOs and critical suppliers.

Ensure robust CMO and supplier qualification, selection, onboarding, ongoing monitoring, and lifecycle governance in partnership with Technical Operations, Supply Chain, Regulatory, Inspection Management, and Quality Systems.

Lead and/or support health authority inspection readiness, pre-approval inspection readiness, CMO inspection support, due diligence assessments, and responses to inspection observations associated with CMC and external operations.

Provide Quality leadership for regulatory submissions and post-approval commitments, including review of relevant CMC sections for INDs, BLAs, MAAs, amendments, supplements, annual reports, and responses to health authority questions.

Develop, implement, and continuously improve CMC QA policies, SOPs, standards, governance processes, and scalable quality infrastructure to support rare and ultrarare disease product development, commercial supply, and portfolio growth.

Model and reinforce a culture of quality, accountability, collaboration, continuous improvement, and patient focus across internal teams and external partners.

Perform other duties as assigned.

Requirements:

Bachelor's degree in life sciences, engineering, pharmacy, chemistry, biotechnology, or a related discipline; advanced degree (MS, PharmD, PhD, or equivalent) preferred.

Typically 15+ years of progressive experience in pharmaceutical, biotechnology, biologics, gene therapy, small molecule, or related regulated industry, with significant experience in CMC Quality Assurance and external manufacturing oversight.

Typically 10+ years of leadership experience within a Quality organization in a FDA/EMA-regulated environment, including experience leading leaders or senior professionals and managing departmental priorities, budgets, and resources.

Demonstrated experience providing quality oversight for CMOs/CDMOs, critical suppliers, and/or outsourced GMP operations across clinical, launch, and commercial lifecycle stages.

Expert knowledge of global GMP requirements and expectations, including FDA, EMA, ICH Q7/Q8/Q9/Q10/Q11/Q12 as applicable, and experience with other regulatory authorities such as MHRA, PMDA, Health Canada, ANVISA, and/or other global agencies.

Strong technical understanding of CMC development and manufacturing across multiple modalities such as biologics, small molecules, oligonucleotides, gene therapy, mRNA, enzymes/proteins, or other advanced/novel therapeutics; direct experience with starting materials, drug substance, and drug product preferred.

Proven ability to lead CMC QA strategy for rapid development, rare disease, ultrarare disease, registration, launch readiness, and commercial operations in a matrixed and/or highly outsourced operating model.

Demonstrated expertise in quality agreements, supplier qualification, deviation/investigation approval, CAPA effectiveness, change control, validation, technology transfer, APQR/PQR, CPV, and quality metrics.

Experience supporting health authority inspections, PAI readiness, regulatory filings, responses to health authority questions, and inspection observation remediation.

Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.

Executive-level communication, influencing, negotiation, and stakeholder-management skills, with the ability to align senior leaders and external partners around pragmatic, compliant, patient-focused solutions.

Demonstrated ability to build, lead, engage, and develop high-performing teams through ambiguity, growth, and organizational change.

Experience with Veeva or other electronic Quality Management Systems preferred; proficiency with Microsoft Word, Excel, PowerPoint, Teams, and Project or equivalent tools required.

Ability to travel up to approximately 20–30% domestically and internationally to Ultragenyx sites, CMOs/CDMOs, suppliers, and regulatory or inspection-related activities, as business needs require.

Physical Demand Requirements:

Primarily office-based role using a computer, phone, and virtual collaboration tools for extended periods.

Ability to work in a hybrid environment and travel to Ultragenyx sites, external manufacturing partners, contract laboratories, supplier sites, and other business locations as needed.

Occasional entry into GMP manufacturing, warehouse, laboratory, or controlled environments may require use of personal protective equipment and adherence to site-specific gowning, safety, and access requirements.
Ability to sit or stand for extended periods and participate in meetings, inspections, walkthroughs, and partner visits.

#LI-KJ1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

Generous vacation time and public holidays observed by the company

Volunteer days

Long term incentive and Employee stock purchase plans or equivalent offerings

Employee wellbeing benefits

Fitness reimbursement

Tuition sponsoring

Professional development plans

Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.

See company reviews

Base pay range

The minimum salary is $294K and the max salary is $363K.

$294K – $363K/yr (Employer provided)

$329K

/yr Median

South San Francisco, CA

If an employer includes a salary or salary range on their job, we display it as "Employer Provided". If a job has no salary data, Glassdoor displays a "Glassdoor Estimate" if available. To learn more about "Glassdoor Estimates," see our FAQ page.

Working here doesn’t have to be a secret

3.4

Recommend to a friend
Approve of CEO
CEO: Emil Kakkis
154 Ratings

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Is your resume a good match?

Use AI to find out how well the skills on your resume fit this job description.

Why Join Us?

Be a hero for our rare disease patients

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

Work Model:

Responsibilities:

Set and execute the CMC QA vision, strategy, operating model, and priorities for External Operations across all Ultragenyx programs and modalities, including starting materials, drug substance, and drug product.

Lead, coach, and develop a high-performing team of approximately 8–12 staff members responsible for program QA and CMO QA oversight; establish clear accountabilities, resource plans, succession plans, and performance expectations.

Ensure external partners operate in compliance with FDA, EMA, ICH, and other applicable global regulatory requirements, Ultragenyx Quality standards, approved regulatory filings, quality agreements, and industry best practices.

Drive proactive, risk-based oversight of external manufacturing quality systems, including deviations, investigations, CAPAs, change controls, complaints, product impact assessments, APR/PQR/APQR, CPV, validation, and tech transfer activities.

Own or oversee quality risk management strategies for external operations, including risk profiles, risk controls, escalation pathways, quality metrics, scorecards, trend reviews, and continuous improvement plans for CMOs and critical suppliers.

Ensure robust CMO and supplier qualification, selection, onboarding, ongoing monitoring, and lifecycle governance in partnership with Technical Operations, Supply Chain, Regulatory, Inspection Management, and Quality Systems.

Lead and/or support health authority inspection readiness, pre-approval inspection readiness, CMO inspection support, due diligence assessments, and responses to inspection observations associated with CMC and external operations.

Provide Quality leadership for regulatory submissions and post-approval commitments, including review of relevant CMC sections for INDs, BLAs, MAAs, amendments, supplements, annual reports, and responses to health authority questions.

Develop, implement, and continuously improve CMC QA policies, SOPs, standards, governance processes, and scalable quality infrastructure to support rare and ultrarare disease product development, commercial supply, and portfolio growth.

Model and reinforce a culture of quality, accountability, collaboration, continuous improvement, and patient focus across internal teams and external partners.

Perform other duties as assigned.

Requirements:

Bachelor's degree in life sciences, engineering, pharmacy, chemistry, biotechnology, or a related discipline; advanced degree (MS, PharmD, PhD, or equivalent) preferred.

Typically 15+ years of progressive experience in pharmaceutical, biotechnology, biologics, gene therapy, small molecule, or related regulated industry, with significant experience in CMC Quality Assurance and external manufacturing oversight.

Typically 10+ years of leadership experience within a Quality organization in a FDA/EMA-regulated environment, including experience leading leaders or senior professionals and managing departmental priorities, budgets, and resources.

Demonstrated experience providing quality oversight for CMOs/CDMOs, critical suppliers, and/or outsourced GMP operations across clinical, launch, and commercial lifecycle stages.

Expert knowledge of global GMP requirements and expectations, including FDA, EMA, ICH Q7/Q8/Q9/Q10/Q11/Q12 as applicable, and experience with other regulatory authorities such as MHRA, PMDA, Health Canada, ANVISA, and/or other global agencies.

Strong technical understanding of CMC development and manufacturing across multiple modalities such as biologics, small molecules, oligonucleotides, gene therapy, mRNA, enzymes/proteins, or other advanced/novel therapeutics; direct experience with starting materials, drug substance, and drug product preferred.

Proven ability to lead CMC QA strategy for rapid development, rare disease, ultrarare disease, registration, launch readiness, and commercial operations in a matrixed and/or highly outsourced operating model.

Demonstrated expertise in quality agreements, supplier qualification, deviation/investigation approval, CAPA effectiveness, change control, validation, technology transfer, APQR/PQR, CPV, and quality metrics.

Experience supporting health authority inspections, PAI readiness, regulatory filings, responses to health authority questions, and inspection observation remediation.

Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.

Executive-level communication, influencing, negotiation, and stakeholder-management skills, with the ability to align senior leaders and external partners around pragmatic, compliant, patient-focused solutions.

Demonstrated ability to build, lead, engage, and develop high-performing teams through ambiguity, growth, and organizational change.

Experience with Veeva or other electronic Quality Management Systems preferred; proficiency with Microsoft Word, Excel, PowerPoint, Teams, and Project or equivalent tools required.

Ability to travel up to approximately 20–30% domestically and internationally to Ultragenyx sites, CMOs/CDMOs, suppliers, and regulatory or inspection-related activities, as business needs require.

Physical Demand Requirements:

Primarily office-based role using a computer, phone, and virtual collaboration tools for extended periods.

Ability to work in a hybrid environment and travel to Ultragenyx sites, external manufacturing partners, contract laboratories, supplier sites, and other business locations as needed.

Occasional entry into GMP manufacturing, warehouse, laboratory, or controlled environments may require use of personal protective equipment and adherence to site-specific gowning, safety, and access requirements.
Ability to sit or stand for extended periods and participate in meetings, inspections, walkthroughs, and partner visits.

#LI-KJ1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

Generous vacation time and public holidays observed by the company

Volunteer days

Long term incentive and Employee stock purchase plans or equivalent offerings

Employee wellbeing benefits

Fitness reimbursement

Tuition sponsoring

Professional development plans

Benefits vary by region and country

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

See company reviews

Base pay range

The minimum salary is $294K and the max salary is $363K.

$294K – $363K/yr (Employer provided)

$329K

/yr Median

South San Francisco, CA

Working here doesn’t have to be a secret

3.4

Recommend to a friend
Approve of CEO
CEO: Emil Kakkis
154 Ratings

Are you open to new opportunities?

121,987 Director, Optical Engineering jobs in United States

Position Summary:

Work Model:

Responsibilities:

Requirements:

Physical Demand Requirements:

Base pay range

Working here doesn’t have to be a secret

Position Summary:

Work Model:

Responsibilities:

Requirements:

Physical Demand Requirements:

Base pay range

Working here doesn’t have to be a secret