At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

Senior Research Associate, Clinical Genomics

Genmab is seeking a highly motivated Senior Research Associate to join the Clinical Genomics team within Translational Sciences, located in Princeton, NJ. The Clinical Genomics team supports translational and clinical development programs by generating high-quality genomic data from patient-derived samples to inform biomarker discovery, patient stratification, disease biology, and response to therapy.

This lab-based role will focus primarily on FFPE tissue processing, DNA extraction, whole exome sequencing workflows, NGS library preparation, sequencing quality assessment, and data delivery support. The successful candidate will have strong hands-on experience with FFPE clinical samples, nucleic acid extraction, Illumina-based sequencing workflows, assay QC, troubleshooting, and cross-functional collaboration. The role may also support FFPE RNA extraction and RNA-seq workflows as needed.

This position requires onsite presence at Genmab’s Princeton, NJ site.

Responsibilities

• Execute FFPE tissue processing, DNA extraction, nucleic acid quantification, quality assessment, and sample preparation for NGS workflows.
• Support whole exome sequencing workflows, including library preparation, sequencing coordination, assay QC, troubleshooting, and documentation.
• Work with limited clinical FFPE tissue samples while applying careful sample handling, input assessment, and tissue-use prioritization.
• Support FFPE RNA extraction and RNA-seq sample preparation workflows as needed.
• Review assay and sequencing QC metrics to ensure data quality and readiness for downstream analysis.
• Coordinate with Bioinformatics and Data Science colleagues to support data handoff, QC review, and preparation of analysis-ready deliverables.
• Maintain accurate documentation of clinical sample workflows using LIMS, ELN, and other tracking systems.
• Contribute to assay optimization, workflow standardization, process improvements, and technology development activities.
• Collaborate with Translational Sciences, Clinical Operations, Pathology, Bioinformatics, and external partners to support timely delivery of clinical genomics data.
• Perform work in alignment with internal quality expectations and GCP-supportive documentation practices.

Requirements

• BS or MS in Biology, Molecular Biology, Genomics, Immunology, Oncology, or a related field, with 3+ years of relevant laboratory experience.
• Strong hands-on experience with FFPE tissue processing, DNA extraction, nucleic acid QC, NGS library preparation, and Illumina sequencing workflows.
• Experience with whole exome sequencing, hybrid-capture NGS assays, or related genomic profiling technologies.
• Experience working with clinical or limited tissue samples in oncology, translational research, pharmaceutical, or biotech settings.
• Hands-on experience with both FFPE RNA extraction and RNA-seq sample preparation workflows is preferred.
• Ability to evaluate assay performance, interpret sequencing QC metrics, troubleshoot technical issues, and clearly communicate results.
• Working knowledge of NGS data quality concepts, including coverage metrics, library complexity, sequencing performance, and batch effects.
• Experience using LIMS, ELN, or other structured sample and laboratory tracking systems.
• Strong organizational skills, attention to detail, and ability to manage multiple time-sensitive workflows.
• Strong interpersonal, written, and verbal communication skills.
• Experience with spatial genomics, multiplex imaging, or additional tissue-based molecular profiling platforms is a plus.

Additional Responsibilities

• Translate project needs into executable clinical genomics workflows.
• Support planning, coordination, and prioritization of clinical sample processing activities.
• Contribute to continuous improvement of FFPE DNA, WES, RNA-seq, and related tissue genomics workflows.
• Participate in project teams, platform discussions, and cross-functional translational research meetings.
• Serve as a technical resource for FFPE tissue genomics workflows and support training of team members as needed.
• Maintain high-quality records to ensure traceability, reproducibility, and readiness for clinical sample data delivery.

For US based candidates, the proposed salary band for this position is as follows:

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives.

When you join Genmab, you’re joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

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Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.