Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.

We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.

At argenx, we are committed to putting the patient first. The Director, US Patient Assistance Program (PAP), will play a critical role in ensuring patients who face financial barriers are able to access therapy through a compliant, scalable, and patient-centered support model.

Role Overview

The Director, US Patient Assistance Program (PAP), will lead the strategy, design, and execution of argenx’s PAP across current and future indications. This individual will partner closely with US Patient Advocacy leadership and cross-functional stakeholders to evolve a best-in-class operating model that supports access today while building a scalable foundation for pipeline expansion.

This role requires both strategic thinking and operational depth. The Director will shape future-state program design while ensuring day-to-day excellence in execution, vendor oversight, compliance, and case management performance.

Key Responsibilities

Strategic Program Leadership

• Partner with Head of Patient Experience COE to define and evolve the long-term vision and operating model for PAP across in-market and pipeline indications

• Design scalable, indication-agnostic program frameworks that support portfolio growth and future launches

• Identify opportunities to optimize the patient journey using operational data, patient insights, and cross-functional feedback

• Anticipate and adapt to changes in regulatory, compliance, reimbursement, and market dynamics

• Support launch readiness planning for new indications requiring PAP support

Program Operations & Execution

• Own end-to-end execution of PAP operations, including intake, eligibility determination, case management workflows, and product fulfillment pathways

• Oversee performance of hub, specialty pharmacy, and third-party vendors; manage SLAs, KPIs, and continuous improvement initiatives

• Establish and maintain SOPs, documentation standards, and quality controls to ensure operational excellence

• Monitor operational metrics and drive performance optimization across patient support pathways

• Manage escalations and complex patient scenarios with urgency, integrity, and a patient-first mindset

Vendor & Cross-Functional Partnership

• Serve as the primary business lead for vendors supporting PAP operations

• Partner closely with Legal, Compliance, Finance, Market Access, Medical, Commercial, and Patient Services teams to ensure alignment and program integrity

• Ensure integration of PAP processes within the broader patient support ecosystem, including benefits investigation, prior authorization, and specialty pharmacy coordination

• Communicate program performance, risks, and opportunities to senior leadership

Compliance & Governance

• Ensure adherence to all applicable laws, regulations, foundation requirements, and internal policies

• Maintain audit readiness and documentation rigor

• Champion a strong compliance mindset across vendors and internal stakeholders

• Identify and report adverse events in accordance with established procedures

Skills, Knowledge & Abilities

• Passion for improving access and supporting patients living with rare and autoimmune diseases

• Ability to operate both strategically and tactically in a growth-stage environment

• Strong analytical skills with the ability to translate data into operational improvements

• Exceptional cross-functional collaboration skills within a matrixed organization

• Comfort working in evolving environments and building structure where it does not yet exist

• Strong communication skills, with the ability to influence and align diverse stakeholders

Requirements

• Bachelor’s Degree required; advanced degree (MBA, MHA, PharmD, or similar) preferred

• 10+ years of pharmaceutical, biotech, healthcare operations, or related experience

• Experience leading patient support, hub, call center, or program operations teams

• Deep knowledge of patient assistance programs, benefits verification, and specialty pharmacy processes

• Experience managing third-party vendors and driving SLA performance

• Strong understanding of compliance requirements, HIPAA, and patient privacy regulations

• Approximately 30% Travel Required

Preferred

• Experience scaling patient programs across multiple indications or supporting launch readiness

• Experience operating in a high-growth biotech environment

• Direct experience with Patient Assistance Programs or charitable foundation models

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For applicants in the United States: The annual base salary hiring range for this position is $184,000.00 - $253,000.00 USD. This range reflects our good faith estimate at the time of posting. Individual compensation is determined using objective, inclusive, and job-related criteria such as relevant experience, skills, demonstrated competencies and internal equity. This means actual pay may differ from the posted range when justified by these factors. Because market conditions evolve, pay ranges are reviewed regularly and may be adjusted to remain aligned with external benchmarks.

This job is eligible to participate in our short-term and long-term incentive programs, subject to the terms and conditions of those plans and applicable policies. It also includes a comprehensive benefits package, including but not limited to retirement savings plans, health benefits and other benefits subject to the terms of the applicable plans and program guidelines.

At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.

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If you require reasonable accommodation in completing your application, interviewing, or otherwise participating in the candidate selection process please contact us at hr.us@argenx.com . Only inquiries related to an accommodation request will receive a response.