Notifications

Ultragenyx
3.4
Executive Director, CMC QA
South San Francisco, CA
$294K - $363K (Employer provided)
Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.…
18d
Ultragenyx
3.4
Executive Director, CMC QA
Novato, CA
$294K - $363K (Employer provided)
Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.…
18d
S3 Shared Service Solutions
3.1
Member Service Representative
New York State
$40K (Employer provided)
Answer high-volume inbound calls and use strong technical proficiency to navigate multiple systems (telephony platform, account servicing tools, CRM, knowledge……
30d+
customer relations jobs in New York State New York State jobs S3 Shared Service Solutions jobs in New York State
S3 Shared Service Solutions salaries customer relations salaries in New York State
Employee reviews at S3 Shared Service Solutions S3 Shared Service Solutions interview experience Working at S3 Shared Service Solutions
State of Washington
3.4
Physician 3 - CRCC
Connell, WA
$246K - $331K (Employer provided)
Unrestricted license to practice medicine in Washington State. Unrestricted DEA license with waiver to prescribe buprenorphine for opioid use disorder.…
30d+
Allied Coop
3.2
Shop Supervisor - Colby
Colby, WI
$47K - $68K (Glassdoor est.)
Provide strategic leadership and oversight of mechanical operations while serving as a working manager actively engaged in hands-on mechanical repair and……
30d+
ProviderTrust
4.3
Primary Source Partnerships Manager
Nashville, TN
$58K - $89K (Glassdoor est.)
Research, outreach drafting, agreement tracking, and pipeline monitoring are supported by AI tools, freeing this individual to concentrate on what AI cannot do:……
7d
H.A. Automotive Systems
2.9
Mandarin Speaking IT Administrator
Troy, MI
$70K (Employer provided)
Easy Apply
We are open to *entry-level candidates with strong IT fundamentals and a willingness to learn*, including Computer Science or related graduates who are eager to……
30d+
CORT
3.3
Senior Tenting Project Manager
Everett, WA
$65K - $85K (Employer provided)
Easy Apply
Valid driver’s license, safe driving record, and reliable transportation for travel between job sites/appointments.…
11d
Freudenberg Group
3.5
Technical Project Engineer - -Static Sealing Solutions North America
Broken Arrow, OK
$94K - $129K (Glassdoor est.)
This role requires advanced technical knowledge of expansion joints, material knowledge, process and engineering tools knowledge and the ability to manage and……
15d
Pacific Dataport Inc
Network Infrastructure Manager
Anchorage, AK
$93K - $145K (Employer provided)
Easy Apply
Valid driver’s license and acceptable driving record, with the ability and willingness to travel within Alaska and work at remote locations.…
24h
Dynamic Air Solutions
Commercial HVAC Field Team Lead - 5K Sign On Bonus
Louisville, KY
Easy Apply
Valid driver's license with acceptable driving record. Journeyman or Master HVAC license [state or local, where applicable].…
30d+
Amazon
3.5
Senior Constructability Engineer, Data Center Design Engineering
Seattle, WA
$137K - $185K (Employer provided)
Optimise the engineering input post design completion - driving consistent roles and responsibilities and accountability.…
6d
Police and Fire Federal Credit Union
3.0
Sr. SecOps Security Engineer
Bensalem, PA
$112K - $169K (Glassdoor est.)
Bachelor’s degree in Computer Science, Information Technology, or a related field. Deploy zero-day threat protection and develop response strategies.…
26d
Korn Ferry
3.3
Pricing Strategy Manager
Corning, NY
$101K - $138K (Employer provided)
Bachelor’s degree in Business, a technical discipline, or a related field. Lead and advance pricing tools within Gorilla Glass to ensure a design that is……
30d+
Archer Mechanical & Maintenance
3.9
Journeyman HVAC/R Technician
Salt Lake City, UT
$45.00 - $55.00 Per Hour (Employer provided)
Easy Apply
Valid driver’s license with a clean MVR - required for operating a company vehicle. _Archer Mechanical specializes in sustainable mechanical and plumbing……
25d
TargetPath
4.4
Amazon Account Manager
Wilsonville, OR
Easy Apply
Bachelor's degree in Business, Marketing, Ecommerce, or a related field preferred; equivalent professional experience considered.…
30d+
FedEx
3.5
Maintenance Technician III - 4+ Years Experience
Sauget, IL
$24.75 - $38.43 Per Hour (Employer provided)
Will interpret electrical or mechanical schematics, manufacturer’s manuals and engineering specifications to troubleshoot, diagnose and repair system faults and……
30d+
Amazon
3.5
Principal Technical Program Manager, Amazon Customer Service
Seattle, WA
$177K - $239K (Employer provided)
Design, launch and own the complex, multi-year QoS program, driving the overall strategy, working backwards plan, execution mechanisms, milestones, and cross-……
24h
ABEC
2.3
Service Engineering Manager
Bethlehem, PA
$107K - $156K (Glassdoor est.)
Experience leading and developing technical service, engineering, or field service teams. Bachelor’s degree in Engineering, Business, or related field.…
30d+
Rehlko
3.1
Sr Project leader - Engineering Systems
Sheboygan, WI
$88K - $111K (Employer provided)
Lead discovery in ambiguous environments (unknown stakeholders, unclear current state, limited documentation) to quickly establish current-state understanding……
14d
Viaero Wireless
3.3
Fiber Engineering Manager
Fort Morgan, CO
$87K - $92K (Employer provided)
Easy Apply
This role is responsible not only for managing current in-house CAD designers and field engineers, but for intentionally expanding internal capabilities and……
30d+
AVSi
Director of Technical Services
Minneapolis, MN
$85K - $115K (Employer provided)
Easy Apply
7–10+ years in technical service operations, field service management, or technical support leadership. This is a *working‑manager* role: actively engaged in……
30d+
Pinnacle Communication Services
3.0
Security Department Manager (NOT Security Guard)
Glendale, CA
$95K - $115K (Employer provided)
Easy Apply
Valid driver's license and ability to travel to client sites as needed. Manage technical quality across new installations, upgrades, and service calls,……
3d
GC&E Systems Group
4.3
Electronic Security Service Technician III
Peachtree Corners, GA
$56K - $78K (Glassdoor est.)
Valid driver’s license and acceptable driving record. Under limited supervision, the Technician demonstrates full technical competence, leads small to medium……
12d
E-Logic
3.2
Project Manager
New York, NY
$90K (Employer provided)
Easy Apply
The Project Manager will lead daily operations, coordinate field teams, manage schedules, ensure compliance with contractual requirements, and serve as the……
30d+
Telecom One, Inc.
Technical Sales & Support Manager
Brookfield, WI
$85K - $105K (Employer provided)
Easy Apply
Experience in technical sales support, technical account management, or customer-facing technical support. Provide technical support for products and services……
30d+
Rippling
3.7
Lead Service Technician
Austin, TX
Easy Apply
Valid driver’s license and ability to travel locally. For eligible field-based roles that require travel, Divcon covers all business travel expenses and……
5d
The Computer Hut
4.0
Technical Services Manager
Little Rock, AR
$70K (Employer provided)
Easy Apply
Must possess and maintain a valid Arkansas driver’s license and present it upon request when performing job duties which require operating a vehicle.…
2d
Ardurra
4.4
BIM / 3D Design Manager (Water / Wastewater – Desalination) – Bilingual Spanish
Miami, FL
$75K - $130K (Glassdoor est.)
Easy Apply
Ardurra is seeking a BIM / 3D Design Manager to lead the communication and coordination of technical production and design execution of large-scale water and……
30d+
Dynamic Air Solutions
Commercial HVAC Field Team Lead - 5K Sign On Bonus
Lexington, KY
Easy Apply
Valid driver's license with acceptable driving record. Journeyman or Master HVAC license [state or local, where applicable].…
10d

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Is your resume a good match?

Use AI to find out how well the skills on your resume fit this job description.

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won't go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

The Executive Director, CMC QA will provide strategic, operational, and technical quality leadership across all Ultragenyx programs inclusive of biologics, small molecule, gene therapy, and ASO. This leader will oversee CMC QA responsibilities spanning program QA and CMO QA for starting materials, drug substance, and drug product, ensuring phase-appropriate and commercially robust quality oversight from development through lifecycle management. The role will lead and develop a team of approximately 8–12 quality professionals, partner closely with Technical Operations, Product Development, Supply Chain, Regulatory, and Quality stakeholders, and represent CMC QA in governance forums, inspections, regulatory submissions, and external partner interactions.

Work Model:

Flex: This role will typically require onsite work 2-3 days each week, or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.

Responsibilities:

Set and execute the CMC QA vision, strategy, operating model, and priorities for External Operations across all Ultragenyx programs and modalities, including starting materials, drug substance, and drug product.

Lead, coach, and develop a high-performing team of approximately 8–12 staff members responsible for program QA and CMO QA oversight; establish clear accountabilities, resource plans, succession plans, and performance expectations.

Ensure external partners operate in compliance with FDA, EMA, ICH, and other applicable global regulatory requirements, Ultragenyx Quality standards, approved regulatory filings, quality agreements, and industry best practices.

Drive proactive, risk-based oversight of external manufacturing quality systems, including deviations, investigations, CAPAs, change controls, complaints, product impact assessments, APR/PQR/APQR, CPV, validation, and tech transfer activities.

Own or oversee quality risk management strategies for external operations, including risk profiles, risk controls, escalation pathways, quality metrics, scorecards, trend reviews, and continuous improvement plans for CMOs and critical suppliers.

Ensure robust CMO and supplier qualification, selection, onboarding, ongoing monitoring, and lifecycle governance in partnership with Technical Operations, Supply Chain, Regulatory, Inspection Management, and Quality Systems.

Lead and/or support health authority inspection readiness, pre-approval inspection readiness, CMO inspection support, due diligence assessments, and responses to inspection observations associated with CMC and external operations.

Provide Quality leadership for regulatory submissions and post-approval commitments, including review of relevant CMC sections for INDs, BLAs, MAAs, amendments, supplements, annual reports, and responses to health authority questions.

Develop, implement, and continuously improve CMC QA policies, SOPs, standards, governance processes, and scalable quality infrastructure to support rare and ultrarare disease product development, commercial supply, and portfolio growth.

Model and reinforce a culture of quality, accountability, collaboration, continuous improvement, and patient focus across internal teams and external partners.

Perform other duties as assigned.

Requirements:

Bachelor's degree in life sciences, engineering, pharmacy, chemistry, biotechnology, or a related discipline; advanced degree (MS, PharmD, PhD, or equivalent) preferred.

Typically 15+ years of progressive experience in pharmaceutical, biotechnology, biologics, gene therapy, small molecule, or related regulated industry, with significant experience in CMC Quality Assurance and external manufacturing oversight.

Typically 10+ years of leadership experience within a Quality organization in a FDA/EMA-regulated environment, including experience leading leaders or senior professionals and managing departmental priorities, budgets, and resources.

Demonstrated experience providing quality oversight for CMOs/CDMOs, critical suppliers, and/or outsourced GMP operations across clinical, launch, and commercial lifecycle stages.

Expert knowledge of global GMP requirements and expectations, including FDA, EMA, ICH Q7/Q8/Q9/Q10/Q11/Q12 as applicable, and experience with other regulatory authorities such as MHRA, PMDA, Health Canada, ANVISA, and/or other global agencies.

Strong technical understanding of CMC development and manufacturing across multiple modalities such as biologics, small molecules, oligonucleotides, gene therapy, mRNA, enzymes/proteins, or other advanced/novel therapeutics; direct experience with starting materials, drug substance, and drug product preferred.

Proven ability to lead CMC QA strategy for rapid development, rare disease, ultrarare disease, registration, launch readiness, and commercial operations in a matrixed and/or highly outsourced operating model.

Demonstrated expertise in quality agreements, supplier qualification, deviation/investigation approval, CAPA effectiveness, change control, validation, technology transfer, APQR/PQR, CPV, and quality metrics.

Experience supporting health authority inspections, PAI readiness, regulatory filings, responses to health authority questions, and inspection observation remediation.

Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.

Executive-level communication, influencing, negotiation, and stakeholder-management skills, with the ability to align senior leaders and external partners around pragmatic, compliant, patient-focused solutions.

Demonstrated ability to build, lead, engage, and develop high-performing teams through ambiguity, growth, and organizational change.

Experience with Veeva or other electronic Quality Management Systems preferred; proficiency with Microsoft Word, Excel, PowerPoint, Teams, and Project or equivalent tools required.

Ability to travel up to approximately 20–30% domestically and internationally to Ultragenyx sites, CMOs/CDMOs, suppliers, and regulatory or inspection-related activities, as business needs require.

Physical Demand Requirements:

Primarily office-based role using a computer, phone, and virtual collaboration tools for extended periods.

Ability to work in a hybrid environment and travel to Ultragenyx sites, external manufacturing partners, contract laboratories, supplier sites, and other business locations as needed.

Occasional entry into GMP manufacturing, warehouse, laboratory, or controlled environments may require use of personal protective equipment and adherence to site-specific gowning, safety, and access requirements.
Ability to sit or stand for extended periods and participate in meetings, inspections, walkthroughs, and partner visits.

#LI-KJ1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

Generous vacation time and public holidays observed by the company

Volunteer days

Long term incentive and Employee stock purchase plans or equivalent offerings

Employee wellbeing benefits

Fitness reimbursement

Tuition sponsoring

Professional development plans

Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.

See company reviews

Base pay range

The minimum salary is $294K and the max salary is $363K.

$294K – $363K/yr (Employer provided)

$329K

/yr Median

South San Francisco, CA

If an employer includes a salary or salary range on their job, we display it as "Employer Provided". If a job has no salary data, Glassdoor displays a "Glassdoor Estimate" if available. To learn more about "Glassdoor Estimates," see our FAQ page.

Working here doesn’t have to be a secret

3.4

Recommend to a friend
Approve of CEO
CEO: Emil Kakkis
154 Ratings

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Ultragenyx

3.4

Executive Director, CMC QA

South San Francisco, CA

$294K - $363K (Employer provided)

Is your resume a good match?

Use AI to find out how well the skills on your resume fit this job description.

Why Join Us?

Be a hero for our rare disease patients

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultraimpact – Make a difference for those who need it most

Work Model:

Responsibilities:

Set and execute the CMC QA vision, strategy, operating model, and priorities for External Operations across all Ultragenyx programs and modalities, including starting materials, drug substance, and drug product.

Lead, coach, and develop a high-performing team of approximately 8–12 staff members responsible for program QA and CMO QA oversight; establish clear accountabilities, resource plans, succession plans, and performance expectations.

Ensure external partners operate in compliance with FDA, EMA, ICH, and other applicable global regulatory requirements, Ultragenyx Quality standards, approved regulatory filings, quality agreements, and industry best practices.

Drive proactive, risk-based oversight of external manufacturing quality systems, including deviations, investigations, CAPAs, change controls, complaints, product impact assessments, APR/PQR/APQR, CPV, validation, and tech transfer activities.

Own or oversee quality risk management strategies for external operations, including risk profiles, risk controls, escalation pathways, quality metrics, scorecards, trend reviews, and continuous improvement plans for CMOs and critical suppliers.

Ensure robust CMO and supplier qualification, selection, onboarding, ongoing monitoring, and lifecycle governance in partnership with Technical Operations, Supply Chain, Regulatory, Inspection Management, and Quality Systems.

Lead and/or support health authority inspection readiness, pre-approval inspection readiness, CMO inspection support, due diligence assessments, and responses to inspection observations associated with CMC and external operations.

Provide Quality leadership for regulatory submissions and post-approval commitments, including review of relevant CMC sections for INDs, BLAs, MAAs, amendments, supplements, annual reports, and responses to health authority questions.

Develop, implement, and continuously improve CMC QA policies, SOPs, standards, governance processes, and scalable quality infrastructure to support rare and ultrarare disease product development, commercial supply, and portfolio growth.

Model and reinforce a culture of quality, accountability, collaboration, continuous improvement, and patient focus across internal teams and external partners.

Perform other duties as assigned.

Requirements:

Bachelor's degree in life sciences, engineering, pharmacy, chemistry, biotechnology, or a related discipline; advanced degree (MS, PharmD, PhD, or equivalent) preferred.

Typically 15+ years of progressive experience in pharmaceutical, biotechnology, biologics, gene therapy, small molecule, or related regulated industry, with significant experience in CMC Quality Assurance and external manufacturing oversight.

Typically 10+ years of leadership experience within a Quality organization in a FDA/EMA-regulated environment, including experience leading leaders or senior professionals and managing departmental priorities, budgets, and resources.

Demonstrated experience providing quality oversight for CMOs/CDMOs, critical suppliers, and/or outsourced GMP operations across clinical, launch, and commercial lifecycle stages.

Expert knowledge of global GMP requirements and expectations, including FDA, EMA, ICH Q7/Q8/Q9/Q10/Q11/Q12 as applicable, and experience with other regulatory authorities such as MHRA, PMDA, Health Canada, ANVISA, and/or other global agencies.

Strong technical understanding of CMC development and manufacturing across multiple modalities such as biologics, small molecules, oligonucleotides, gene therapy, mRNA, enzymes/proteins, or other advanced/novel therapeutics; direct experience with starting materials, drug substance, and drug product preferred.

Proven ability to lead CMC QA strategy for rapid development, rare disease, ultrarare disease, registration, launch readiness, and commercial operations in a matrixed and/or highly outsourced operating model.

Demonstrated expertise in quality agreements, supplier qualification, deviation/investigation approval, CAPA effectiveness, change control, validation, technology transfer, APQR/PQR, CPV, and quality metrics.

Experience supporting health authority inspections, PAI readiness, regulatory filings, responses to health authority questions, and inspection observation remediation.

Strong quality risk management capability and proficiency with root cause analysis, risk assessment, trend analysis, and decision-making tools.

Executive-level communication, influencing, negotiation, and stakeholder-management skills, with the ability to align senior leaders and external partners around pragmatic, compliant, patient-focused solutions.

Demonstrated ability to build, lead, engage, and develop high-performing teams through ambiguity, growth, and organizational change.

Experience with Veeva or other electronic Quality Management Systems preferred; proficiency with Microsoft Word, Excel, PowerPoint, Teams, and Project or equivalent tools required.

Ability to travel up to approximately 20–30% domestically and internationally to Ultragenyx sites, CMOs/CDMOs, suppliers, and regulatory or inspection-related activities, as business needs require.

Physical Demand Requirements:

Primarily office-based role using a computer, phone, and virtual collaboration tools for extended periods.

Ability to work in a hybrid environment and travel to Ultragenyx sites, external manufacturing partners, contract laboratories, supplier sites, and other business locations as needed.

Occasional entry into GMP manufacturing, warehouse, laboratory, or controlled environments may require use of personal protective equipment and adherence to site-specific gowning, safety, and access requirements.
Ability to sit or stand for extended periods and participate in meetings, inspections, walkthroughs, and partner visits.

#LI-KJ1 #LI-Hybrid

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

Generous vacation time and public holidays observed by the company

Volunteer days

Long term incentive and Employee stock purchase plans or equivalent offerings

Employee wellbeing benefits

Fitness reimbursement

Tuition sponsoring

Professional development plans

Benefits vary by region and country

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

See company reviews

Base pay range

The minimum salary is $294K and the max salary is $363K.

$294K – $363K/yr (Employer provided)

$329K

/yr Median

South San Francisco, CA

Working here doesn’t have to be a secret

3.4

Recommend to a friend
Approve of CEO
CEO: Emil Kakkis
154 Ratings

17,481 Technical escalation manager jobs in United States

Position Summary:

Work Model:

Responsibilities:

Requirements:

Physical Demand Requirements:

Base pay range

Working here doesn’t have to be a secret

Position Summary:

Work Model:

Responsibilities:

Requirements:

Physical Demand Requirements:

Base pay range

Working here doesn’t have to be a secret