Pros
I've worked at Partners for over 8 years and it has been an amazing place to work. The benefits are great (they only cost me $1.56/week for medical, dental, and vision) and the work is great. I think people forget why you work at a place like Partners. Do you work there because it's a job? To help with patient care? Both? I work in Partners eCare and while it has been demanding, I don't lose site of the overall purpose of the work which is to improve patient care. Sure there are areas of improvement, but I think the job here is what we make of it.
Cons
The work can be demanding and hard on work/life balance but most managers listen when you need a break. HR set the stage of the program as did upper management so if you're not paying attention then it's your fault.