Pros
Orbitz is the top eCommerce company to work for in Chicago. That may sound inflated, but we're not talking about Seattle or San Francisco. There are very few global e-commerce companies in the area, so the competition is admittedly thin. However, the thrill and responsibility of working for a company that gets a million uniques a day is exceptional. The workforce is on the whole young, ambitious, and bright. It is not nearly as nimble as a startup, but that is counterbalanced by having the brand presence and resources to establish partnerships and leverage technologies that you otherwise can't get with a small company. The office location is insanely convenient for both downtown and suburban residents (in the Ogilvie Transportation building). The office itself is a modern open-concept layout that is very nice to work in. And there's a ping pong table, an internet company must-have.
Cons
It's a big company (almost 1000 globally) and thus there is some inevitable red tape and slowness to react with industry trends. The travel industry is an uber-competitive one, and there is pressure from senior leadership on down to analysts to get better margins, increase efficiency, and continually come up with innovative ideas. The economy forced some layoffs, and that is unpleasant and nerve-wracking to go through. There have been re-orgs than one would expect (1/year since I've been here) and that can cause churn and uncertainty.