Pros
RTI does a pretty good job at the whole work-life balance thing; fairly good benefits (health insurance plans and 401(k) are both pretty strong, etc.) owing to its status as a non-profit; job security is generally very good, even in times of economic uncertainty; generally a very collegial atmosphere.
Cons
Far too much management- especially senior management, most of whom don't seem to know much about the work their people actually do; little to no management support; poor coordination between the various business units; poor coordination between the academics/researchers and the support staff; when layoffs do happen, they are often targeted at lower-level positions, regardless of job performance; budget pressures in recent years have led to cuts in benefits and training; pay is uneven in that some people (typically researchers) appear to be quite well paid but other positions (typically support staff) appear to make less than market.