Pros
Definitely a fun environment to work in, flexible schedule (barring any, rare, emergencies), and very good benefits. The staff are a lot of really excited people who want to do great things for comic books and solve big problems. Integration with Amazon offers a lot of really cool benefits as far as what can be used to solve problems. Working with Amazon also allows for a lot of potential upward movement and opportunity to work with a lot of diverse and intelligent people.
Cons
comiXology is incredibly ambitious and because of that there's a lot to be done with stretched resources. Team sizes are good but 2+ years into the Amazon acquisition, only some of the growing pains are gone. The turnover of long time staff cashing in post-aqusition has left some knowledge lost which tends to lead to overhauls of small pieces of infrastructure with unforeseen effects causing other small pieces to malfunction.