Genentech employees working as Principal Program Manager in US have attributed a compensation and benefits rating of 4.6 out of 5 stars, based on 2 ratings. This is 2% higher than the average of Principal Program Manager professionals at Genentech worldwide.
The salary trajectory of a Principal Program Manager ranges between locations and employers. The salary starts at $104,984 per year (estimate) and goes up to $238,736 per year (estimate) for the highest level of seniority.
The estimated average salary for a Principal Program Manager at Genentech is $220,929 per year or $106 per hour, but some professionals have reported earning up to roughly $337,440 per year (90th percentile). The typical pay range is between $179,110 (25th percentile) and $277,180 (75th percentile) annually. This is based on 9 salaries submitted by Genentech Principal Program Manager professionals on Glassdoor, as of Jul 2026.
Principal Program Manager professionals typically earn between $86 and $133 per hour.
Principal Program Manager professionals typically earn between $14,926 and $23,098 monthly.