As with any large company, you will work with (and sometimes under) people who are not good leaders or managers, or just coasting along. Most of the time these kinds of things tend to work themselves out, but sometimes it can take longer than you think.
Some people may not like the amount of ambiguity or change that happens due to the competitive landscape we are in. (Reorgs happen more than once a year.)
International travel policy was changed to remove business class travel. The cost savings are obvious, but 8+ hour flights in economy can be brutal.
If I had the choice to do it all over again, I would absolutely work here again despite the inherent 'cons' that come with any company.