WOW this is too easy so I'll keep it to the first ten things that pop into my head...
1. Inadequate PC Hardware/software
2. Poor management that overlooks and promotes bad behavior including violating HIPAA regulations
3. Lack of understanding of what is required to get the job done
4. Lack of knowledge of work
5. Lack of focus on important issues such as insurance contracting problems
6. Lack of coordination with projects
7. TERRIBLE pay, as a lead I make less than $10/hr
8. ICARE principles are a JOKE!!! A member of the ICARE committee routinely disregards all rules
9. HR team that is more interested in making friends than following trough on complaints
10. Inadequate training; the lab department doesn't even have a trainer!!!