Senior management, especially in corporate IT are heading down the path towards outsourcing all their skilled talent in the name of perceived short term gains. Those in management make decisions without even understanding the effects on the businesses they support, and then are rewarded for their shrewd choices.
Yearly re-orgs ensure that you can never become comfortable with your management team, associates, or responsibilities which lead to wasted years where the business essentially accomplishes nothing while they re-align objectives.
Many people in more entry level IT roles are taking on responsibilities well above their pay grade but see no recognition or path for advancement. While positions are posted internally, the company chooses to ignore applicants and hire from outside the company without any consideration made whatsoever. It didn't used to be this way but changes in the last 2-3 years in HR or others within recruitment seem to actively dissuade top performers from growth opportunities. This talent which should be the backbone of the company 10 years from now, instead leaves the company and becomes an asset that they can never get back.
IT business roles are heavily silo'd leading to situations where change management processes for 10 minute tasks require hours of approvals and setup amongst teams.
Morale throughout IT and other business areas is especially poor in recent years which is leading to a mass exodus of the talented people who see the writing on the wall. For a service company like McKesson, the loss of its most talented people is going to lead to dire consequences in the coming years.